The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites
Trial ID or NCT#
Status
Purpose
To compare the efficacy of branched-chain amino acid in serum albumin level in cirrhotic patients with ascites.
Official Title
The Effect of Branched-chain Amino Acid on the Improvement of Serum Albumin Level in Cirrhotic Patients With Ascites: A Multi-center, Randomized, Double-blind, Placebo-controlled, Investigator Initiated Clinical Trial
Eligibility Criteria
- * Age ≥ 19 and ≤ 70 years;* Presence of liver cirrhosis* Serum albumin level ≤ 3.5g/dl, ultrasound or CT scan confirmed ascites (≥Grade 1)* No administration of diuretics and BCAA within the past 1 week* Voluntary consent to take part in this trial
- * Child-Pugh score \> 12* Having been diagnosed as HCC within the past 5 years* Serum creatinine \> 1.5mg/dl* Serum bilirubin \> 5.0mg/dl* Presence of such complications as SBP, or hepatic encephalopathy(West Haven grade ≥ 3)* Patients who experienced organ failure by acute exacerbation of liver cirrhosis within the past 1 month* Presence of serious cardiac or respiratory disease* Contraindicated to either diuretics or BCAA* Having commenced anti-viral treatment against hepatitis C, B within the past 1 month* Pregnant or lactating women* Chronic alcohol taker* Woman patients who do not agree to the contraception from baseline to 12 month* Unsuitable patients judged by investigator* Patients participating in another clinical trial within 1 month
Investigator(s)
Contact us to find out if this trial is right for you.
Contact
W.Ray Kim, Professor
650-725-6511
View on ClinicalTrials.gov