Treatment Trial for Psychogenic Nonepileptic Seizures
Trial ID or NCT#
Status
Purpose
The investigators propose that patients who receive targeted pharmacotherapy (sertraline) or focused psychotherapy (cognitive behavioral therapy-informed psychotherapy (CBT-ip) for NES) or combined treatment (CBT-ip + sertraline) will report fewer nonepileptic seizures (NES) compared to patients who receive community care / treatment as usual (TAU). The purpose of this study is to provide pilot testing and data to inform the future multicenter randomized controlled trial based on the hypothesis.
Official Title
Medication and Psychotherapy Treatment Trial for Psychogenic Nonepileptic Seizures
Eligibility Criteria
- * Video electroencephalogram (EEG) confirmed diagnosis of NES* Have at least one nonepileptic seizure per month* Able to complete self report symptom scales* Not receiving optimized sertraline
- * Equivocal EEG findings* using monoamine oxidase inhibitors (MAOIs), pimozide, or sumatriptan* allergy/sensitivity to sertraline* current alcohol/drug dependence* serious medical illness requiring current hospitalization
Investigator(s)
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Contact
Jessica Hawkins
6507238323
View on ClinicalTrials.gov