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New insights into Entamoeba histolytica pathogenesis
New insights into Entamoeba histolytica pathogenesis CURRENT OPINION IN INFECTIOUS DISEASES Baxt, L. A., Singh, U. 2008; 21 (5): 489-494Abstract
Entamoeba histolytica is an important global pathogen and a leading cause of parasitic death worldwide. This article summarizes significant research findings over the last year.Efforts have focused primarily on identification of novel virulence determinants in E. histolytica, transcriptional profiling during tissue invasion and stage conversion, and characterization of basic cell biological processes. Additionally, new techniques for gene silencing have been identified.A comprehensive examination of the parasite lifestyle on a whole genome level has been undertaken, allowing identification of new virulence genes and signaling pathways and processes relevant to amebic biology.
View details for DOI 10.1097/QCO.0b013e32830ce75f
View details for Web of Science ID 000259078900007
View details for PubMedID 18725798
View details for PubMedCentralID PMC2688559