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Coding and noncoding genomic regions of Entamoeba histolytica have significantly different rates of sequence polymorphisms: Implications for epidemiological studies
Coding and noncoding genomic regions of Entamoeba histolytica have significantly different rates of sequence polymorphisms: Implications for epidemiological studies JOURNAL OF CLINICAL MICROBIOLOGY Bhattacharya, D., Haque, R., Singh, U. 2005; 43 (9): 4815-4819Abstract
To evaluate genetic variability among Entamoeba histolytica strains, we sequenced 9,077 bp from each of 14 isolates. The polymorphism rates from coding and noncoding regions were significantly different (0.07% and 0.37%, respectively), indicating that these regions are subject to different selection pressures. Additionally, single nucleotide polymorphisms (SNPs) potentially associated with specific clinical outcomes were identified.
View details for DOI 10.1128/JCM.43.9.4815-4819.2005
View details for Web of Science ID 000232020400078
View details for PubMedID 16145147
View details for PubMedCentralID PMC1234137