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Principles and philosophy of modeling in biomedical research
Principles and philosophy of modeling in biomedical research FASEB JOURNAL Massoud, T. F., Hademenos, G. J., Young, W. L., Gao, E. Z., Pile-Spellman, J., Vinuela, F. 1998; 12 (3): 275-285Abstract
Despite widespread applications in biomedical research, the role of models and modeling is often controversial and ill understood. It is usual to find that fundamental definitions, axioms, and postulates used in the modeling process have become tacit assumptions. What is essential, however, is a clear vision of the fundamental principles of modeling. This is even more compelling for new and emerging interdisciplinary fields that use techniques from previously separate scientific disciplines. This article outlines and reviews the central nature and philosophy of modeling, the rules that govern it, and its underlying key integral relationship to the 'scientific method'. A comprehensive understanding of these issues is indispensable to successful research and meaningful progress in all facets of biomedicine.
View details for Web of Science ID 000072305500016
View details for PubMedID 9580086